Oncast Money · Closing Bell

AI bubble odds jump after Nasdaq rout

· Fact-checked before it aired. Unconfirmed claims from this segment are not shown.

The entire full-time police department in Milner, Georgia, resigned after Mayor Craig Timmons admitted placing a tracker on Police Chief Lamar Bunn's truck. The city manager also resigned.

Karyopharm Therapeutics filed for Chapter 11 bankruptcy protection on Nov. 2, 2026, and announced a proposed merger with Ayrmid Ltd with up to $55 million in financing.

Karyopharm's Xpovio (selinexor) maker filed for Chapter 11 under a restructuring plan to merge with Ayrmid, owner of Gamida Cell, backed by up to $55 million in new financing.

Karyopharm has confirmed a Chapter 11 bankruptcy filing and proposed a court-supervised merger with Ayrmid, with up to $55 million in committed financing.

CNBC reports that OpenAI's CFO said the company will keep investing in AI data centers despite election results.

CNBC reports that President Trump said Stephen Miller will replace Susie Wiles as White House chief of staff, following the midterm elections.

CNBC reports that Sen. Chris Murphy of Connecticut was released from the hospital after a stroke and will miss Senate votes for several weeks.

CNBC reports that Abdulrahman Alfozan, a Saudi national charged with planting a recording device at OpenAI, pleaded not guilty.

Fact-check

VERIFIED TRUE

The entire full-time police department in Milner, Georgia, resigned after Mayor Craig Timmons admitted placing a tracker on Police Chief Lamar Bunn's truck. The city manager also resigned.

BREAKING: Entire police department in Georgia resigns after the town's mayor allegedly begins surveilling the police chief & tracking his movements.

Original post · @Polymarket

[wsbtv.com](https://www.wsbtv.com/news/local/georgia-mayor-admits-tracking-police-chiefs-vehicle-entire-full-time-police-force-resigns/JLUDDOPMBNEOJG572TOQNJI5Y

VERIFIED TRUE

Karyopharm Therapeutics filed for Chapter 11 bankruptcy protection on Nov. 2, 2026, and announced a proposed merger with Ayrmid Ltd with up to $55 million in financing.

🚨 Karyopharm Therapeutics filed for Chapter 11 bankruptcy protection on November 2, 2026, and announced a proposed merger with Ayrmid Ltd. #mmsm #myeloma #MedEd #medtwitter #USMIRC @USMIRCNEWS @OpenMedKate @Larvol @US_HMC @oncodaily https://t.co/mgaJoxh3m7

Original post · Al-Ola A Abdallah MD (USMIRC) (@Abdallah81MD)

The Pharma Letter NAMES: Karyopharm Therapeutics = biotech company, ticker KPTI; Ayrmid Ltd = healthcare company; KPTI = Karyopharm stock ticker

VERIFIED TRUE

Karyopharm's Xpovio (selinexor) maker filed for Chapter 11 under a restructuring plan to merge with Ayrmid, owner of Gamida Cell, backed by up to $55 million in new financing.

Chapter 11, then a merger: Xpovio (selinexor) maker @Karyopharm has filed for bankruptcy protection under a restructuring plan to merge with Ayrmid, owner of @GamidaCellTx, backed by up to $55 million of new financing. https://t.co/1VbyVb5hmC #Biotech #Oncology

Original post · The Pharma Letter (@ThePharmaLetter)

The Pharma Letter NAMES: Xpovio = selinexor, Karyopharm's cancer drug; GamidaCellTx = Gamida Cell, a cell therapy company

VERIFIED TRUE

Karyopharm has confirmed a Chapter 11 bankruptcy filing and proposed a court-supervised merger with Ayrmid, with up to $55 million in committed financing.

KPTI: Bankruptcy filing confirmed $KPTI has officially filed for Chapter 11 bankruptcy protection. Karyopharm has proposed a court supervised merger with Ayrmid and secured commitments for up to $55M in financing. The business plans to continue operating, but shareholders face

Original post · Green Wick Energy (@NoldeaReally)

The Pharma Letter NAMES: KPTI = Karyopharm Therapeutics stock ticker

VERIFIED TRUE

CNBC reports that OpenAI's CFO said the company will keep investing in AI data centers despite election results.

OpenAI will keep investing in AI data centers despite election results, CFO tells CNBC - Voters across the country on Tuesday voiced their support for candidates who have pledged to place restrictions on data center development.

Original post · CNBC

[cnbc.com](https://www.cnbc.com/2026/11/06/open-ai-data-centers-election.html) NAMES: OpenAI = artificial intelligence company; CFO = chief financial officer

VERIFIED TRUE

CNBC reports that President Trump said Stephen Miller will replace Susie Wiles as White House chief of staff, following the midterm elections.

Trump says Stephen Miller to replace Susie Wiles as White House chief of staff - Trump revealed the shake-up three days after Democrats' landslide victory in the midterm elections, winning majority control of the House and Senate.

Original post · CNBC

[cnbc.com](https://www.cnbc.com/2026/11/06/trump-stephen-miller-wiles-chief-of-staff.html) NAMES: Stephen Miller = longtime Trump adviser; Susie Wiles = outgoin

VERIFIED TRUE

CNBC reports that Sen. Chris Murphy of Connecticut was released from the hospital after a stroke and will miss Senate votes for several weeks.

Sen. Chris Murphy released from hospital after stroke, will miss votes for 'several weeks' as he rehabs - The Connecticut Democrat Murphy has been discussed as a possible candidate for the White House in 2028.

Original post · CNBC

[cnbc.com](https://www.cnbc.com/2026/11/06/chris-murphy-stroke-hospital-senate.html) NAMES: Chris Murphy = Democratic U.S. Senator from Connecticut

VERIFIED TRUE

CNBC reports that Abdulrahman Alfozan, a Saudi national charged with planting a recording device at OpenAI, pleaded not guilty.

OpenAI bugging suspect Alfozan pleads not guilty - Saudi national Abdulrahman Alfozan is charged with planting a recording device in a conference room at artificial intelligence giant OpenAI.

Original post · CNBC

[cnbc.com](https://www.cnbc.com/2026/11/06/openai-bugging-alfozan-saudi.html) NAMES: Alfozan = Abdulrahman Alfozan, Saudi national charged in the OpenAI bugging

Sources

What the hosts said

ATwenty-seven percent. That's the number Unusual Whales says Polymarket now puts on an AI bubble collapse by mid-2027.
BAfter one rough Nasdaq close, the crowd is ready to call the top.
AThe post on X claims a two point three trillion dollar Nasdaq one hundred wipeout.
BThat's a number usually reserved for a full-blown crisis.
ANo official market close has put out that figure. The claim is moving faster than the data.
BBut the odds themselves moved, and that's the story. Prediction markets are just fear with a price tag.
AThey're not fear with a price tag. They're a betting line, and they swing on rumors.
BSo what? The market paid a massive premium for AI, and now wants that revenue.
AThe revenue was never the near-term driver. Data center buildout is. That hasn't stopped.
BIt hasn't stopped, but the big tech names all traded together on the way down.
AOne down day is not a bubble bursting. Bubbles don't ring a bell at twenty-seven percent.
BExactly! The fact that we're even pricing a collapse at twenty-seven percent is the warning.
AWe priced a recession before the last few selloffs, and then the market ripped higher.
BOh, come on. That's survivorship bias.
AIt's memory. Prediction markets overreact.
BSome of those people got run over.
AMy point is, I'm not calling an AI bubble off a Polymarket screenshot and an unverified wipeout number.
BFine. But if those odds keep climbing after Monday, I'll be a lot less calm.
AAnd that's a real test. We'll see it in the actual close.
BDifferent corner of the market: Karyopharm Therapeutics just filed for Chapter eleven.
AThis is a commercial-stage cancer drug maker, Xpovio, going into restructuring to merge with Ayrmid.
BThe Pharma Letter reports up to fifty-five million dollars in new financing is backing the deal.
AChapter eleven, then a merger. For shareholders, that usually means the value gets reset.
BThe company says it plans to keep operating. The drug isn't gone.
ARight. This is a balance sheet problem, not a science problem.
BIt's still a warning for small-cap biotech. Cash is tight.
AAnd the ticker, KPTI, just got a lot more volatile.
BVolatile might be the kindest word for a bankruptcy ticker.
AFair. But the restructuring could give it a new owner and a cleaner book.
BI've seen that movie before. The sequel is never kind to the old equity.
AWe'll leave the sequel prediction to Hollywood.
BSpeaking of central banks keeping their options open, Bank of Japan Governor Ueda gave the market a line today.
AZerohedge posted on X that Ueda said the BOJ may be obliged to use quantitative easing tools again someday.
BThe account's follow-up was two words: 'Oh you will.'
AThat part's editorial. No official transcript of the exact quote is out yet.
BBut the idea alone matters. Japan spent years trying to normalize, and the bond market has been twitchy.
AIf the BOJ is even hinting at QE again, global bond traders will hear it.
BThat's the part people forget: once a central bank opens that door, it never really closes it.
AThe Fed opened it in two thousand eight, then again in twenty twenty. Here we are.
BAnd that's my problem with Ueda saying 'may be obliged.' It's a trial balloon.
AIt's central bank communication. They test the market, then they watch the reaction.
BWell, if the bond reports are right, some of that reaction may already be showing up in Japanese government bonds.
AThe key word is 'may.' Not 'will.' Not 'soon.' Maybe not ever.
BBut after the AI trade gets shaky, central banks love a good safety net.
AThey love the option. The market loves the ambiguity less.
BNo, the market loves the ambiguity until it turns into a policy error.
AOn that, we can agree.

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